UGM graduate student has scheduled research on early diagnosis of Alzheimer's disease | Ural State Medical University

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UGM graduate student planned research on early diagnosis of Alzheimer's disease 30-12-2019 News

Graduate student of the Ural State Medical University (UGM) Anton Kodintsev He began preparation for the study, the purpose of which is the development of the express method of early diagnosis of Alzheimer's disease. For diagnosis, it is assumed to analyze changes in the concentration of beta-amyloid and tau protein in saliva.

Effective methods of diagnosing Alzheimer's disease at an early stage today no, noted the codings. "Interventions at an early stage are the most effective and theoretically, they can strongly slow down the progression of the pathological process itself in the brain," said the graduate student. Now doctors face patients when there is already a manifestization of the disease, and the therapeutic window is lost. "I had a thought, why not see the proteins, which are the main morphological substrates of this disease, in saliva? Compare these indicators in the blood and measure these indicators with an enzyme immunoassay analysis, "the graduate student of the first year of study is explained in the specialty" Clinical Medicine ".

The Kodartsev project was held in the final of the innovation contest "Melnik", whose winner will receive a grant of 500 thousand rubles for the implementation of his research. According to the graduate student, his work is at the initial stage, and the main problem is a financial question due to the need for reagents. Negotiations are being underway with reagent suppliers, the scales are validated to divide patients into groups. It is planned to conduct a study on the basis of the Central Research Laboratory of Umbum.

"Ideally need some cool spectrometry – it is quite difficult to implement it. I also want to add that in most countries there are such research teams, branches – one I can do little so that it is effective, "said Koditsev. The novice researcher noted that she would try to achieve success in his scientific work – despite the difficulties and pitfalls that may arise on the path to the goal.